An Introduction to Systematic Reviews of Diagnostic Test Accuracy
Background: As for any healthcare intervention, medical tests require thorough evaluation. Identifying the accuracy of a test is a key step in the evaluation process. Understanding other ways in which tests
As for any healthcare intervention, medical tests require thorough evaluation. Identifying the accuracy of a test is a key step in the evaluation process. Understanding other ways in which tests affect the clinical management of patients is also important – a new test may be more acceptable to patients, easier to administer, or provide a faster diagnosis or treatment.
The accuracy of a test is a measure of how well it differentiates those with a disease or condition from those who do not. Different, sometimes complex, study designs can be used to evaluate diagnostic accuracy. Measures of accuracy are also not fixed properties of a test and may not be transferable across different populations and settings. A systematic review aims to provide an overview of currently available evidence about a test’s diagnostic accuracy. A basic understanding of study designs, potential sources of bias, and factors that might affect the applicability of a study’s findings, are essential to ensure that the included studies answer a relevant review question.
To provide an introduction to systematic reviews of diagnostic test accuracy.
The objective of this workshop is to provide an understanding of study designs to evaluate the accuracy of a test and the essential components of a systematic review of diagnostic test accuracy.
In this course participants will be enabled to:
- describe the key differences between systematic reviews of interventions and systematic reviews of test accuracy,
- be aware of study designs used to estimate and compare the accuracy of tests,
- be aware of the sources of bias and variation that occur in test accuracy studies,
- be aware of the approaches used for meta-analysis of test accuracy and interpretation of meta-analytic estimates.
The workshop does not cover how to conduct a meta-analysis of test accuracy studies.
Date: 29th April 2024
Time: 10.00 am – 12.00 pm
Places: 30 places available for individuals who are resident on the island of Ireland
Fee: General €50; Student €25
Skill level: Introductory
Target Audience: Healthcare professionals, academics, researchers, decision makers, librarians, information specialists, and Evidence Synthesis Ireland fellows and teaching faculty who would like to learn more about DTA reviews
Jac Dinnes, PhD
Senior Research Fellow in Test Evaluation
Test and Prediction group, Institute of Applied Research,
University of Birmingham UK
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(Monday) 10:00 am - 12:00 pm UTC